2- hydroxy-1, 5-naphthidine - Names and Identifiers
2- hydroxy-1, 5-naphthidine - Physico-chemical Properties
Molecular Formula | C8H6N2O
|
Molar Mass | 146.15 |
Density | 1.267±0.06 g/cm3(Predicted) |
Melting Point | 258 °C |
Boling Point | 391.8±42.0 °C(Predicted) |
pKa | 11.29±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
2- hydroxy-1, 5-naphthidine - Introduction
1,5-Naphthyridin-2-ol(1,5-Naphthyridin-2-ol) is an organic compound with the chemical formula C11H8N2O. Its properties are as follows:
1. Appearance: 1,5-Naphthyridin-2-ol is a white crystalline solid.
2. Solubility: 1,5-Naphthyridin-2-ol is soluble in most organic solvents, such as ethanol, dichloromethane, etc., but it is difficult to dissolve in water.
3. Melting point: The melting point of 1,5-Naphthyridin-2-ol is about 161-164°C.
4. Stability: 1,5-Naphthyridin-2-ol is relatively stable at room temperature.
1,5-Naphthyridin-2-ol can be used in a variety of applications, including:
1. chemical reagents: can be used as reagents in organic synthesis, involved in esterification, acylation and other organic reactions.
2. Cosmetics: Due to its special structure and properties, 1,5-Naphthyridin-2-ol can be used in cosmetics, with soft skin and antioxidant effects.
3. Drug research: 1,5-Naphthyridin-2-ol, as a drug intermediate, can be used to synthesize biologically active compounds.
The method for preparing 1,5-Naphthyridin-2-ol mainly includes the following steps:
1. p-methylaniline and acetylacetonate alcohol are subjected to condensation reaction to obtain naphthyridone.
2. Naphthyridinone undergoes lactonization reaction under acid catalysis to generate 1,5-Naphthyridin-2-ol.
When using 1,5-Naphthyridin-2-ol, you need to pay attention to the following safety information:
1. Avoid inhaling 1,5-Naphthyridin-2-ol dust or vapor, and wear appropriate personal protective equipment, such as protective glasses and gloves.
2. After contact with 1,5-Naphthyridin-2-ol, the contaminated skin should be thoroughly cleaned, and the work area should be cleaned in time after the operation.
3. When storing 1,5-Naphthyridin-2-ol, it should be sealed and kept in a dry and cool place, away from fire and flammable materials.
4. when conducting experiments or synthesis, operate in strict accordance with laboratory rules and regulations and comply with relevant operational safety instructions.
Please note that the above information is for reference only. For specific safety information, please refer to the safety data sheet provided by the laboratory or manufacturer.
Last Update:2024-04-09 21:21:28